When it comes to talking about the best neighborhoods to live in New York City, Manhattan’s Upper East Side neighborhood has consistently made an appearance in such discussions. If there was, however, any doubt on the exclusivity, grandeur and richness of the homes in the Upper East Side, then this particular news should serve to dispel any fears to the contrary. In Forbes’ annual list of America’s most expensive zip codes, this classic New York City enclave, with its 10065 zip code boasting a median home price of $6.5 million, has trumped other localities in the country to be called the most expensive neighborhood in America.